Concierge medicine for patients with hypermobility, from physicians who understand.

Our family has three generations of individuals living with hypermobile Ehlers-Danlos Syndrome (hEDS). We built the clinic we wish we had, for our family and for yours.

We are a family of multi-disciplinary physicians that bring a personal perspective and understanding of treating patients with hypermobility, MCAS and Dysautonomia.

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Our physicians are licensed in the state of New York.

At this time, we are only able to see patients in New York.

Visits are available via Telehealth (for patients physically located in New York at time of care) or in-person at our office in Albany, New York.

For me, this is personal.

My name is Dr. Rani Gandham. I’m a practicing pediatrician in the state of New York who, through lived experience, became a rehabilitation expert in conditions such as dysautonomia, mast cell activation syndrome (MCAS), cervical and thoracic outlet-related issues, and hypermobility-related syndromes for all ages.

This work is personal. My adult son (now 34) and my young granddaughter (now 4) both have hypermobile Ehlers-Danlos Syndrome (hEDS), along with associated autonomic, venous compression, and mast cell issues.

When my son became sick, we struggled to get answers. After finally receiving a diagnosis, we traveled across the country seeing top specialists…regenerative medicine providers, GI doctors, rheumatologists, orthopedists, cardiologists, endocrinologists. Many of these clinicians were thoughtful and often correct in their own domains. But what was missing was integration.

Each system was being evaluated in isolation, even though the symptoms were clearly interacting. Nervous system dysregulation (POTS, dysautonomia, fatigue), immune activation (MCAS, histamine intolerance), and connective tissue instability do not operate independently. They amplify one another. Treating one without accounting for the others often leads to incomplete results.

From that experience, a framework emerged: a structured way of organizing treatment that prioritizes how symptoms interact across systems, the order in which those systems are addressed, and the amount of physiologic load a patient can safely tolerate. That framework helped my son get back to his normal life, and now it forms the basis of our medical practice: one that integrates detailed medical history, imaging, strength & rehabilitation guidance, pharmacological and natural treatment of MCAS & Dysautonomia, and most importantly…longitudinal tracking of symptoms through high-touch care for our patients.

Our clinic’s care team is able to provide robust, comprehensive care reflective of the complex nature of hypermobility and its related conditions. My husband is an ophthalmologist whose office provides retinal and optic nerve imaging to flag signs of intracranial hypertension—a hidden but often occurring issue in patients with autonomic dysfunction. My son, now a strength and rehab coach, brings both professional training and lived experience to the rehabilitation journey.

We built this practice so you can truly have a clinical home…where your care is coordinated and your whole picture is understood.

~ Dr. Rani Gandham

About our Team

Conditions we diagnose or treat

This clinic is designed for patients with overlapping, complex conditions—especially those whose symptoms span multiple systems. That includes:

  • Hypermobility and Hypermobile Ehlers-Danlos Syndrome

  • Autonomic dysfunction (e.g., POTS, temperature instability, fatigue syndromes)

  • Mast cell activation and histamine-related issues

  • GI motility issues, acid reflux, gastritis, SIBO, and gut-brain axis disruption

  • Spinal instability (Thoracic Outlet Syndrome, Craniocervical Instability, SI Joint dysfunction)

  • Pediatric and multi-generational hypermobility presentations

  • Pain and Chronic Fatigue

Meet your care team

  • A woman smiling, wearing a beaded dress and large earrings, with a blurred background.

    Dr. Rani Gandham, M.D.

    Physician for Hypermobility, Dysautonomia & MCAS

  • A smiling man with glasses and dark hair, wearing a pink shirt and maroon sweater, sitting on a sofa in a room with a window in the background.

    Dr. Sai Gandham, M.D.

    Ophthalmic Evaluation for Intracranial Pressure

  • A man speaking into a microphone at an event with a colorful geometric patterned wall in the background.

    Kasey Gandham

    Strength & Rehabilitation Coach

A person's hands typing on a laptop keyboard with a stethoscope resting on the wooden surface in the foreground.

We are a high-attention concierge medicine family practice.

This is a low-volume, high-attention concierge medicine practice. We limit patient capacity to no more than 100 patients per year, so I can provide an exceptional level of hands-on care to each patient and continue to care for my own family’s needs with hEDS as well.

Learn about our patient services